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\u73af\u4fdd\u578b\u805a\u4e59\u4e8c\u9187\u53ef\u4ee5\u4f5c\u4e3a\u98df\u54c1\u7684\u589e\u7a20\u5242\u3001\u7a33\u5b9a\u5242\u3001\u4fdd\u6e7f\u5242\u7b49\uff0c\u6539\u5584\u98df\u54c1\u7684\u53e3\u611f\u548c\u54c1\u8d28\u3002\u5b83\u53ef\u4ee5\u50cf\u4e00\u4f4d\u5de7\u624b\u7684\u201c\u53a8\u5e08\u201d\uff0c\u8ba9\u98df\u7269\u66f4\u52a0\u7f8e\u5473\u53ef\u53e3\u3002<\/li>\n<li><strong>\u7eba\u7ec7\u9886\u57df\uff1a<\/strong> \u73af\u4fdd\u578b\u805a\u4e59\u4e8c\u9187\u53ef\u4ee5\u4f5c\u4e3a\u7eba\u7ec7\u54c1\u7684\u67d4\u8f6f\u5242\u3001\u6297\u9759\u7535\u5242\u3001\u6da6\u6ed1\u5242\u7b49\uff0c\u63d0\u9ad8\u7eba\u7ec7\u54c1\u7684\u8212\u9002\u6027\u548c\u8010\u7528\u6027\u3002\u5b83\u53ef\u4ee5\u50cf\u4e00\u4f4d\u8d34\u5fc3\u7684\u201c\u88c1\u7f1d\u201d\uff0c\u8ba9\u8863\u7269\u66f4\u52a0\u67d4\u8f6f\u8212\u9002\u3002<\/li>\n<li><strong>\u65e5\u5316\u9886\u57df\uff1a<\/strong> \u73af\u4fdd\u578b\u805a\u4e59\u4e8c\u9187\u53ef\u4ee5\u7528\u4e8e\u6d17\u6da4\u5242\u3001\u6e05\u6d01\u5242\u7b49\u65e5\u5316\u4ea7\u54c1\u4e2d\uff0c\u63d0\u9ad8\u4ea7\u54c1\u7684\u6e05\u6d01\u529b\u548c\u6eb6\u89e3\u529b\u3002\u5b83\u53ef\u4ee5\u50cf\u4e00\u4f4d\u52e4\u52b3\u7684\u201c\u6e05\u6d01\u5de5\u201d\uff0c\u8ba9\u6211\u4eec\u7684\u751f\u6d3b\u73af\u5883\u66f4\u52a0\u5e72\u51c0\u6574\u6d01\u3002<\/li>\n<li><strong>\u5de5\u4e1a\u9886\u57df\uff1a<\/strong> \u73af\u4fdd\u578b\u805a\u4e59\u4e8c\u9187\u53ef\u4ee5\u4f5c\u4e3a\u6da6\u6ed1\u5242\u3001\u5206\u6563\u5242\u3001\u6eb6\u5242\u7b49\uff0c\u7528\u4e8e\u5404\u79cd\u5de5\u4e1a\u751f\u4ea7\u8fc7\u7a0b\u4e2d\uff0c\u63d0\u9ad8\u751f\u4ea7\u6548\u7387\u548c\u4ea7\u54c1\u8d28\u91cf\u3002\u5b83\u53ef\u4ee5\u50cf\u4e00\u4f4d\u9ad8\u6548\u7684\u201c\u5de5\u7a0b\u5e08\u201d\uff0c\u52a9\u529b\u5de5\u4e1a\u53d1\u5c55\u3002<\/li>\n<li><strong>\u519c\u4e1a\u9886\u57df\uff1a<\/strong> \u73af\u4fdd\u578b\u805a\u4e59\u4e8c\u9187\u53ef\u4ee5\u4f5c\u4e3a\u519c\u836f\u7684\u52a9\u5242\u3001\u80a5\u6599\u7684\u7f13\u91ca\u5242\u7b49\uff0c\u63d0\u9ad8\u519c\u836f\u548c\u80a5\u6599\u7684\u5229\u7528\u7387\uff0c\u51cf\u5c11\u73af\u5883\u6c61\u67d3\u3002\u5b83\u53ef\u4ee5\u50cf\u4e00\u4f4d\u667a\u6167\u7684\u201c\u519c\u592b\u201d\uff0c\u5475\u62a4\u7740\u6211\u4eec\u7684\u571f\u5730\uff0c\u4fdd\u969c\u7cae\u98df\u5b89\u5168\u3002<\/li>\n<\/ul>\n<p><strong>\u73af\u4fdd\u578b\u805a\u4e59\u4e8c\u9187\u7684\u4ea7\u54c1\u53c2\u6570\u201c\u5927\u63ed\u79d8\u201d<\/strong><\/p>\n<p>\u4e3a\u4e86\u8ba9\u5927\u5bb6\u66f4\u6df1\u5165\u5730\u4e86\u89e3\u73af\u4fdd\u578b\u805a\u4e59\u4e8c\u9187\uff0c\u6211\u4eec\u6765\u770b\u4e00\u4e9b\u5e38\u89c1\u7684\u4ea7\u54c1\u53c2\u6570\u3002\u4ee5\u4e0b\u8868\u683c\u5217\u51fa\u4e86\u4e00\u4e9b\u5e38\u7528\u7684\u73af\u4fdd\u578b\u805a\u4e59\u4e8c\u9187\u7684\u5178\u578b\u89c4\u683c\u53ca\u5176\u5e94\u7528\uff1a<\/p>\n<table>\n<thead>\n<tr>\n<th>\u4ea7\u54c1\u578b\u53f7<\/th>\n<th>\u5e73\u5747\u5206\u5b50\u91cf (g\/mol)<\/th>\n<th>\u5916\u89c2<\/th>\n<th>\u7279\u70b9<\/th>\n<th>\u5178\u578b\u5e94\u7528<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>PEG-200<\/td>\n<td>190-210<\/td>\n<td>\u65e0\u8272\u6db2\u4f53<\/td>\n<td>\u4f4e\u5206\u5b50\u91cf\uff0c\u826f\u597d\u7684\u6eb6\u89e3\u6027\uff0c\u4e0e\u591a\u79cd\u6eb6\u5242\u76f8\u5bb9<\/td>\n<td>\u5316\u5986\u54c1\u4fdd\u6e7f\u5242\u3001\u533b\u836f\u4e2d\u95f4\u4f53\u3001\u6eb6\u5242<\/td>\n<\/tr>\n<tr>\n<td>PEG-400<\/td>\n<td>380-420<\/td>\n<td>\u65e0\u8272\u6db2\u4f53<\/td>\n<td>\u6eb6\u89e3\u6027\u597d\uff0c\u6bd2\u6027\u4f4e\uff0c\u523a\u6fc0\u6027\u5c0f<\/td>\n<td>\u53e3\u670d\u6db2\u4f53\u5236\u5242\u3001\u8f6f\u818f\u57fa\u8d28\u3001\u98df\u54c1\u6dfb\u52a0\u5242<\/td>\n<\/tr>\n<tr>\n<td>PEG-600<\/td>\n<td>570-630<\/td>\n<td>\u65e0\u8272\u6db2\u4f53\/\u534a\u56fa\u4f53<\/td>\n<td>\u6c34\u6eb6\u6027\u597d\uff0c\u5177\u6709\u6da6\u6ed1\u6027<\/td>\n<td>\u533b\u836f\u6da6\u6ed1\u5242\u3001\u7eba\u7ec7\u54c1\u67d4\u8f6f\u5242\u3001\u5316\u5986\u54c1\u7a33\u5b9a\u5242<\/td>\n<\/tr>\n<tr>\n<td>PEG-1000<\/td>\n<td>950-1050<\/td>\n<td>\u767d\u8272\u56fa\u4f53<\/td>\n<td>\u826f\u597d\u7684\u6210\u819c\u6027\uff0c\u4e73\u5316\u80fd\u529b<\/td>\n<td>\u533b\u836f\u5305\u8863\u6750\u6599\u3001\u5316\u5986\u54c1\u589e\u7a20\u5242\u3001\u7eba\u7ec7\u5370\u67d3\u52a9\u5242<\/td>\n<\/tr>\n<tr>\n<td>PEG-2000<\/td>\n<td>1900-2100<\/td>\n<td>\u767d\u8272\u56fa\u4f53<\/td>\n<td>\u826f\u597d\u7684\u6c34\u6eb6\u6027\u548c\u751f\u7269\u76f8\u5bb9\u6027\uff0c\u5e38\u7528\u4e8e\u86cb\u767d\u8d28\u4fee\u9970<\/td>\n<td>\u86cb\u767d\u8d28\u836f\u7269PEGylation\u3001\u751f\u7269\u4f20\u611f\u5668\u3001\u7ec4\u7ec7\u5de5\u7a0b\u652f\u67b6<\/td>\n<\/tr>\n<tr>\n<td>PEG-4000<\/td>\n<td>3600-4400<\/td>\n<td>\u767d\u8272\u56fa\u4f53<\/td>\n<td>\u4f18\u5f02\u7684\u589e\u7a20\u6027\u80fd\uff0c\u826f\u597d\u7684\u6210\u578b\u6027<\/td>\n<td>\u7247\u5242\u7c98\u5408\u5242\u3001\u6813\u5242\u57fa\u8d28\u3001\u5316\u5986\u54c1\u6210\u819c\u5242<\/td>\n<\/tr>\n<tr>\n<td>PEG-6000<\/td>\n<td>5400-6600<\/td>\n<td>\u767d\u8272\u56fa\u4f53<\/td>\n<td>\u589e\u7a20\u6548\u679c\u663e\u8457\uff0c\u5177\u6709\u4e00\u5b9a\u7684\u6da6\u6ed1\u6027<\/td>\n<td>\u6d17\u6da4\u5242\u589e\u7a20\u5242\u3001\u9676\u74f7\u6210\u578b\u52a9\u5242\u3001\u5851\u6599\u6539\u6027\u5242<\/td>\n<\/tr>\n<tr>\n<td>PEG-8000<\/td>\n<td>7000-9000<\/td>\n<td>\u767d\u8272\u56fa\u4f53<\/td>\n<td>\u9ad8\u5206\u5b50\u91cf\uff0c\u80fd\u5f62\u6210\u7a33\u5b9a\u7684\u51dd\u80f6\uff0c\u4fdd\u6c34\u6027\u597d<\/td>\n<td>\u7f13\u91ca\u836f\u7269\u57fa\u8d28\u3001\u9762\u819c\u57fa\u8d28\u3001\u519c\u4e1a\u4fdd\u6c34\u5242<\/td>\n<\/tr>\n<tr>\n<td>PEG-10000<\/td>\n<td>9000-11000<\/td>\n<td>\u767d\u8272\u56fa\u4f53<\/td>\n<td>\u66f4\u9ad8\u7684\u5206\u5b50\u91cf\uff0c\u53ef\u5f62\u6210\u66f4\u575a\u56fa\u7684\u51dd\u80f6\uff0c\u9002\u7528\u4e8e\u9ad8\u7c98\u5ea6\u9700\u6c42<\/td>\n<td>\u9ad8\u7ea7\u9762\u819c\u57fa\u8d28\u3001\u751f\u7269\u533b\u7528\u6750\u6599\u3001\u65b0\u578b\u7f13\u91ca\u7cfb\u7edf<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong>\u73af\u4fdd\u578b\u805a\u4e59\u4e8c\u9187\u7684\u201c\u672a\u6765\u4e4b\u8def\u201d<\/strong><\/p>\n<p>\u73af\u4fdd\u578b\u805a\u4e59\u4e8c\u9187\u4f5c\u4e3a\u4e00\u79cd\u5177\u6709\u5de8\u5927\u6f5c\u529b\u7684\u7eff\u8272\u5316\u5de5\u4ea7\u54c1\uff0c\u5176\u672a\u6765\u53d1\u5c55\u524d\u666f\u5e7f\u9614\u3002\u968f\u7740\u4eba\u4eec\u73af\u4fdd\u610f\u8bc6\u7684\u4e0d\u65ad\u63d0\u9ad8\uff0c\u4ee5\u53ca\u5bf9\u53ef\u6301\u7eed\u53d1\u5c55\u7406\u5ff5\u7684\u6df1\u5165\u8df5\u884c\uff0c\u73af\u4fdd\u578b\u805a\u4e59\u4e8c\u9187\u5fc5\u5c06\u5728\u66f4\u591a\u9886\u57df\u53d1\u6325\u91cd\u8981\u4f5c\u7528\u3002<\/p>\n<p>\u672a\u6765\uff0c\u73af\u4fdd\u578b\u805a\u4e59\u4e8c\u9187\u7684\u53d1\u5c55\u65b9\u5411\u4e3b\u8981\u5305\u62ec\u4ee5\u4e0b\u51e0\u4e2a\u65b9\u9762\uff1a<\/p>\n<ul>\n<li><strong>\u539f\u6599\u6765\u6e90\u591a\u5143\u5316\uff1a<\/strong> \u8fdb\u4e00\u6b65\u5f00\u53d1\u5229\u7528\u751f\u7269\u8d28\u8d44\u6e90\uff0c\u4f8b\u5982\u7ea4\u7ef4\u7d20\u3001\u6728\u8d28\u7d20\u7b49\uff0c\u62d3\u5bbd\u73af\u4fdd\u578b\u805a\u4e59\u4e8c\u9187\u7684\u539f\u6599\u6765\u6e90\uff0c\u964d\u4f4e\u751f\u4ea7\u6210\u672c\uff0c\u63d0\u9ad8\u53ef\u6301\u7eed\u6027\u3002<\/li>\n<li><strong>\u751f\u4ea7\u5de5\u827a\u7eff\u8272\u5316\uff1a<\/strong> \u7814\u53d1\u66f4\u52a0\u9ad8\u6548\u3001\u73af\u4fdd\u7684\u751f\u4ea7\u5de5\u827a\uff0c\u51cf\u5c11\u80fd\u6e90\u6d88\u8017\u548c\u5e9f\u7269\u6392\u653e\uff0c\u5b9e\u73b0\u6e05\u6d01\u751f\u4ea7\u3002<\/li>\n<li><strong>\u5e94\u7528\u9886\u57df\u62d3\u5c55\u5316\uff1a<\/strong> 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